Technological aspects of development of a new drug in tablets called "Lavaflam" and its pharmacoeconomic evaluation

Abstract

Hepatobiliary system diseases are actual medical and social problem in the world. Important issue is the development of a new complex of herbal medicine and its pharmacoeconomic study. Development of the technological scheme of the new drug in tablets called «Lavaflam»; analysis of the Ukraine pharmaceutical market of the analogues of «Lavaflam»; determination of socioeconomic accessibility of medicine called «Lavaflam» and its analogs, pharmacoeconomic advantages of «Lavaflam» compared with its analogs. The material of the study was dry concentrate of Helichrysum arenarium (Flamin) and Lavender oil; Ukraine pharmaceutical market of the drugs for the treatment of hepatobiliary system diseases; average retail price data of medicines published in the weekly journal «Pharmacy» in Ukraine in February, 2017; the average salary in Ukraine. Methods: average daily adult dose of the drugs included in the study was calculated as the average manufacturer recommended daily dose for adults (AMRDDA); calculation of socioeconomic coefficients of accessibility of included in the study drugs: solvency adequacy ratio (Ca.s.); cost minimization analysis, NNTcoefficient. The technological scheme of the drug in tablets «Lavaflam» was developed for treatment of hepatobiliary system diseases. 1 tablet of «Lavaflam» contains 50 mg of Flamin and 20 mg of Lavender oil. In the Ukraine pharmaceutical market an analog of «Lavaflam» was found. This medicine is called «FlaminZdorovia». The cost of AMRDDA of «Lavaflam» was 5.91 UAH, of «Flamin-Zdorovia» – 7.42 UAH. When studying the socioeconomic accessibility coefficients it was found: «Lavaflam» is more accessible for the population by 26% compared to «Flamin-Zdorovia». Using the drug «Lavaflam» can reduce cost of pharmacotherapy by 25%. A new complex herbal drug in tablets called «Lavaflam» which contains combination of dry concentrate of Helichrysum arenarium (Flamin) and Lavender oil was developed. It was established that «Lavaflam» had socioeconomic and pharmacoeconomic advantages compared to its analog called «Flamin-Zdorovia».