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http://dspace.nuph.edu.ua/handle/123456789/15243
Полная запись метаданных
Поле DC | Значение | Язык |
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dc.contributor.author | Kyslychenko, O. A. | - |
dc.contributor.author | Protska, V. V. | - |
dc.contributor.author | Zhuravel, I. O. | - |
dc.contributor.author | Hutsol, V. V. | - |
dc.contributor.author | Кисличенко, О. А. | - |
dc.contributor.author | Кисличенко, А. А. | - |
dc.contributor.author | Журавель, І. О. | - |
dc.contributor.author | Журавель, И. А. | - |
dc.contributor.author | Гуцол, В. В. | - |
dc.contributor.author | Процька, В. В. | - |
dc.date.accessioned | 2018-04-28T11:25:22Z | - |
dc.date.available | 2018-04-28T11:25:22Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | The determination of qualitative composition and quantitative content of steroidal compounds in Hosta plantaginea and Hosta lancifolia plant raw material / O. A. Kyslychenko , V. V. Protska, I. O. Zhuravel, V. V. Hutsol // Journal of Pharmacy Research. - 2018. - Vol. 12, Issue 3. - Р. 408-413. | uk_UA |
dc.identifier.uri | http://dspace.nuph.edu.ua/handle/123456789/15243 | - |
dc.description.abstract | Introduction: Hosta species are used as antibacterial and anti-inflammatory agents in Far East countries. Many studies conducted by Chinese scientists testify about 50 steroid compounds in these plants composition. These compounds, according to the researchers’ opinion, show anti-inflammatory and cytostatic activity. Materials and Methods: Qualitative composition and quantitative content of steroidal compounds in Hosta plantaginea and Hosta lancifolia rhizomes with roots, leaves, and flowers were determined by gas chromatography technique. Results and Discussions: As the result of the study, 13 compounds of steroidal structure were found in H. plantaginea rhizomes with roots at a total amount of 103 mg/kg. Only five compounds were detected in leaves and six compounds in flowers. The total amount of the analyzed compounds equaled 312 mg/kg and 114 mg/kg, respectively, for the plant raw material listed above. Six compounds of steroidal structure were founds in both rhizomes with roots and flowers of H. lancifolia. Their total amount equaled 39 mg/kg and 32 mg/kg for rhizomes with roots and flowers, respectively. H. lancifolia leaves contain five identified steroids at the amount of 55 mg/kg. All the analyzed types of plant raw material contained campesterol, stigmasterol, and β-sitosterol at a high amount. The highest content of these compounds was determined in H. plantaginea leaves. It equaled 27 mg/kg, 124 mg/kg, and 131 mg/kg, respectively, for each compound mentioned above. Gitogenin was detected only in H. plantaginea rhizomes with roots at the amount of 36 mg/kg. Conclusions: The obtained data can be used for the development of plant raw material quality control procedures as well as for the development of new drugs on its basis. | uk_UA |
dc.language.iso | en | uk_UA |
dc.subject | gas chromatography | uk_UA |
dc.subject | steroidal compounds | uk_UA |
dc.subject | Hosta lanceolata | uk_UA |
dc.subject | Hosta plantaginea | uk_UA |
dc.title | The determination of qualitative composition and quantitative content of steroidal compounds in Hosta plantaginea and Hosta lancifolia plant raw material | uk_UA |
dc.type | Article | uk_UA |
Располагается в коллекциях: | Наукові публікації кафедри фармакогнозiї та нутриціології |
Файлы этого ресурса:
Файл | Описание | Размер | Формат | |
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индия2018-скопус.pdf | 1,36 MB | Adobe PDF | Просмотреть/Открыть |
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