Search for earch for potential AFI in a series of derivatives of 1-4-methyl-5,7-dichloro-9-hydrazine acridines using in silico technologies

Abstract

The synthesis of new potentially active pharmaceutical ingredients by modification of methyl halogen hydrazinoacridines was carried out experimentally in laboratory conditions. In order to optimise the experimental study of various types of biological activity and the level of their predicted toxicity, in silico computer modelling methods were used with the help of "Way2Drug pharmaexpert online" and "Molinspiration Cheminformatics Software".