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Browsing by Author Severina, H. I.

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Showing results 1 to 20 of 22  next >
Issue DateTitleAuthor(s)
2021Affinity prediction of perspective anticonvulsant API to human adenosine receptorsSeverina, H. I.; Vlasov, S. V.; Prokopenko, Y. S.; Georgiyants, V. A.
2023Construction of new antimicrobial agents based on thieno[2,3-d]pyrimidinesVlasov, S. V.; Vlasova, O. D.; Severina, H. I.; Georgiyants, V. A.
2020Design, synthesis, in vivo and in silico anticonvulsant activity studies of derivatives of 6-amino-4-hydroxy-2-thio-pyrimidineSeverina, H. I.; Skupa, O. O.; Voloshchuk, N. I.; Khairulin, A. R.; Georgiyants, V. A.
2024Determination of affinity of tetrazole derivatives to microsomal prostaglandin synthaseEnnoussi, A.; Severina, H. I.; Енуссі, А.; Северіна, Г. І.
2024Determination of molecular mechanisms of anti-inflammatory activity of a [1,2,4]triazolo[1,5-c]quinazolinе derivativeKultenko, M. V.; Severina, H. I.; Культенко, М. В.; Северіна, Г. І.
2023Determination of the mechanism of concomitant antiinflammatory activity in a new anticonvulsant agent - a pyrazolopyrimidine derivativeBskri, A.; Severina, H. I.
2022Development of antimicrobial agents in the series of amides of 4-oxo-5-methylthieno[2,3-d]pyrimidine-6- carboxylic acidVlasov, S. V.; Vlasov, V. S.; Severina, H. I.; Plys, S. V.; Georgiyants, V. A.
2021Development of HPLC determination of related substances in a new CNC agent – 1-(4-methoxyphenyl)-5-[2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxo-ethyl]pyrazolo[3,4-d]pyrimidin-4-oneSeverina, H. I.; Golovchenko, O. S.; Kolisnik, O. V.; Georgiyants, V. A.
2020Molecular docking, ADMET study and in vivo pharmacological research of N-(3,4-dimetoxyphenyl)-2-{[2-methyl-6-(pyridine-2-yl)-pyrimidin-4-yl]thio} acetamide as a promising anticonvulsantSeverina, H. I.; Skupa, O. O.; Voloshchuk, N. I.; Kovalenko, S. M.; Georgiyants, V. A.; Севєріна, Г. І.; Скупа, О. О.; Волощук, Н. І.; Коваленко, С. М.; Георгіянц, В. А.
2023New potent Trmd inhibitors from the series of thieno[2,3-d]pyrimidin-3(4H)-yl)-N-arylacetamidesVlasov, S. V.; Vasylchenko, V. S.; Severina, H. I.
2024Polypharmacological drug-like molecules from the 2,5-dimethyl-4-oxo-3,4-dihydrothieno[2,3-D]pyrimidine-6-carboxamide seriesVlasov, S. V.; Severina, H. I.; Borysov, O. V.; Vlasova, O. D.; Georgiyants, V. A.; Abu Sharkh, A. I. M.; Власов, С. В.; Северіна, Х. І.; Борисов, О. В.; Власова, О. Д.; Георгіянц, В. А.; Абу Шарх, А. І. М.
2024Prediction of antagonism to nmda receptors by biologically active substances of Matricaria discoidea DC. Synthesis and study of a tetrazole-5-thiole derivativeGergalo, A. V.; Severina, H. I.; Гергало, А. В.; Северіна, Г. І.
2023Prediction of gabaergic mechanism of action of acetamide derivative 6-(pyridinyl-2)-pyrimidine-4-thioneZouhri, B.; Severina, H. I.
2024Prediction of the ability of new 1,2,4-triazole derivatives to inhibit cyclooxygenase-2Moulk Ellah, Taha; Severina, H. I.; Моулк Елла, Таха; Северіна, Г. І.
2024Synthesis and study of a tetrazole-5-thiole derivativeVorona, S. O.; Zabolotska, O. V.; Severina, H. I.; Ворона, С. О.; Заболотська, О. В.; Северіна, Г. І.
2021Synthesis of 1-acetamide derivatives of N-[(2,4-dichlorophenyl)methyl]-2-(2,4-dioxo-1H-quinazolin-3-yl)acetamide as new anticonvulsant agentsWassim M. El Kayal; Severina, H. I.; Amjad abu Shark; Georgiyants, V. A.
2023Synthesis, docking study and antimicrobial activity evaluation of pyridyl amides of thieno[2,3-d]pyrimidine-4-carboxylic acidVlasov, S. V.; Severina, H. I.; Vlasova, O.; Borysov, O.; Shynkarenko, P.; Golovchenko, O. S.; Konechnyi, Y.; Georgiyants, V. A.
2020Synthesis, docking study, and pharmacological evaluation of S-acetamide derivatives of 4,6-dimethyl-2-thiopyrimidine as anticonvulsant agentsSeverina, H. I.; Skupa, O. O.; Voloshchuk, N. I.; Georgiyants, V. A.; Сєвєріна, Г. І.; Скупа, О. О.; Волощук, Н. І.; Георгіянц, В. А.; Северина, А. И.; Скупая, О. О.; Волощук, Н. И.; Георгиянц, В. А.
2024Synthesis, in silico and in vitro antimicrobial activity of N-(benzyl)-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxamidesVlasov, S. V.; Borysov, O. V.; Severina, H. I.; Vlasov, V. S.; Abu Sharkh, AI. M.; Georgiyants, V. A.; Власов, С. В.; Борісов, О. В.; Северіна, Г. І.; Власов, В. С.; Абу Шарк, Ам. І.; Георгіянц, В. А.
2019Synthesis, in vivo and in silico anticonvulsant activity studies of new derivatives of 2-(2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)acetamideEl Kayal, W. M.; Shtrygol, S. Yu.; Zalevskyi, S. V.; Shark, Amjad abu; Tsyvunin, V. V.; Kovalenko, S. M.; Bunyatyan, N. D.; Perekhoda, L. O.; Severina, H. I.; Georgiyants, V. A.
Showing results 1 to 20 of 22  next >