Please use this identifier to cite or link to this item:
Title: Synthesis and In Silico Research of Derivatives of 3-allyl-4-(R-phenyl)-N-(R1-phenyl)thiazole-2-imine
Authors: Perekhoda, L. O.
Suleiman, M. M.
Sych, I. A.
Yaremenko, V. D.
Перехода, Л. А.
Перехода, Л. О.
Сулейман, М. М.
Сич, І. А.
Сыч, И. А.
Яременко, В. Д.
Keywords: derivatives of 3-allyl-4-(R-phenyl)-N-(R1-phenyl)-thiazole-2-imine;synthesis;molecular docking
Issue Date: 2017
Bibliographic description (Ukraine): Synthesis and in silico research of derivatives of 3-allyl-4-(R-phenyl)-N-(R1-phenyl)thiazole-2-imine / L. O.Perekhoda at all. // Der Pharma Chemica. - 2017. - № 9(13). - P. 95-98.
Abstract: The synthesis of those new derivatives of 3-allyl-4-(R-phenyl)-N-(R1-phenyl)-thiazole-2-imine was conducted which consist substituted aromatic radicals. Structure of the compounds synthesized has proved by means of a comprehensive use of modern physical and chemical methods of analysis. In silico research has been conducted of the potential molecular mechanisms of cardioprotective action of the obtained substances with the method of a soft molecular docking, and recommendations to the rational design of the ligands have been made.
Appears in Collections:Наукові публікації кафедри медичної хiмiї

Files in This Item:
File Description SizeFormat 
DPC-9-13-95.pdf342,49 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.