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http://dspace.nuph.edu.ua/handle/123456789/17554| Title: | Molecular and crystal structure of methyl 4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylate |
| Authors: | Shishkina, S. V. Шишкіна, С. В. Ukrainets, I. V. Українець, І. В. Hamza, G. M. Grinevich, L. A. Гріневич, Л. О. |
| Keywords: | 1,2-benzothiazine derivatives;molecular and crystal structure;hydrogen bonding;stacking interaction |
| Issue Date: | 2018 |
| Publisher: | Acta Cryst. |
| Bibliographic description (Ukraine): | Molecular and crystal structure of methyl 4-methyl-2,2-dioxo-1 H -2λ6,1-benzothiazine-3-carboxylate / S. Shishkina, I. Ukrainets, G. Hamza, L. Grinevich // Acta Crystallographica. – 2018. – Vol. 74. – P. 1129-1301. |
| Abstract: | The title compound, C11H11NO4S, possesses weak analgesic properties and is a source compound for the synthesis of highly active analgesic and antiinflammatory compounds. The benzothiazine ring adopts a conformation intermediate between twist-boat and sofa. The ester substituent is turned towards the endocyclic double bond because of steric repulsion. In the crystal, the molecules form columns along the [001] direction, bound by N—H O hydrogen bonds and stacking interactions. |
| URI: | http://dspace.nuph.edu.ua/handle/123456789/17554 |
| Appears in Collections: | Наукові публікації кафедри фармацевтичної хімії |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Acta-E-2018.pdf | 388,41 kB | Adobe PDF | View/Open |
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