Mathematical Design of the Experiment in the Development of Technology of Beeswax Obtaining from Propolis

Abstract

In present material the development of the technology of purified beeswax obtaining from propolis, which meets modern physical-chemical and therapeutic requirements, using a various models of mathematical design of the experiment has been shown. In this work a petroleum-ether fraction of propolis containing a beeswax product was used. While analyzing of the obtained fraction, lipids and some other high- molecular compounds of unqualified structure are extracted in parallel, as well as an insignificant number of the γ-pyrone derivatives. In this connection, the development of the condition of beeswax obtaining from this fraction, which is maximally purified from the related substances, was reasonable. For this purpose a series of classical methods of fractionally differentiated extraction followed by fractions evaporation in a vacuum was used. In addition, methods of precipitation using a some organic solvents were used. The optimal conditions of the technology of purified beeswax obtaining from propolis have been determined by methods of mathematical design.

У цьому матеріалі описана розробка технології очищення бджолиного воску з прополісу, який відповідає сучасним фізико-хімічним і терапевтичним вимогам, використовуючи різні моделі математичного дизайну експерименту. Оптимальні умови технології отримання очищеного бджолиного воску з прополісу були визначені методи математичного проектування.

В связи с этим была разработана методология очищения бельгийского восхождения от Прополиса, а затем проведено научное исследование, посвященное лечению и лечению детей, а также модные математические модели эксперимента. Оптимальное умение и технологическая оценка очищенного бхолиного восстания прополису були визационные методы математического проекта