Identification of Hormonal Status in Rats' Blood with Diseases of Soft Tissues of Parodontium

Abstract

Identification of hormonal status of rats' blood with periodontal diseases was presented in this paper. The necessity of identification of parathyroid hormone level and calcitonin in this group of rats was determined. The highest level of parathyroid hormone was detected in rats with gingivitis that can indicate defects in bony tissue of parodintium, activation of osteoclasts and resorption. The smallest level of parathyroid hormone was observed in rats with dental alveolitis. It also indicates defects of matebolism in connective tissue and it is impotant to indicate adaptive mechanisms tension and loss of adaptation reservoir. Analogical correlation was detected during investigation of calcitonin level during dental alveolitis, periodontitis and gingivitis. Identification of parathyroid hormone level and calcitonin in rats' blood indicates the significance of hormonal factor in pathogenetic mechanisms of the development of metabolic imbalance. Regulation of parathyroid hormone in blood of rats will indicate normalization of metabolism of connective tissue during periodontal diseases. One of the main symtoms development in soft tissues of paradontium is morphological changes of relative area of trabecula and enlargement of intratrabecular space.