Rheology-based substantiation of a gel-former choice for vaginal gel

Abstract

Aim: The purpose of this work is to select a gel former in the vaginal gel. Methods: The structural-mechanical properties were determined using the Rheolab QC rheometer by Anton Paar produced in Austria, which meets the requirements of ISO 3219 standard. Results: The rheological parameters of gel samples with different gel formers have been studied. It has been established that the sample based on Aristoflex AVC has the highest index of the destroyed structure viscosity and the relaxation period, unlike other samples, which allows it to be selected as a gel forming component in the vaginal gel. Conclusions: Aristoflex AVC was selected as a gel forming component in the vaginal gel.