Synthesis of a Magnetite Nanoparticle System for use in Drugs with Magnetic Properties

Abstract

Synthesis of magnetite particles was performed by chemical coprecipitation in alkaline medium (pH = 10-11) using the solutions of sodium hydroxide, potassium hydroxide and 25% ammonium hydroxide. The use of an excess solution of ammonium hydroxide allows obtaining a system of magnetite particles, the saturation magnetization of which exceeds almost three times this parameter for particles synthesized using alkali solutions. It was found that the synthesis should be carried out with the use of excess of 1.75 iron (II) salt in ammonium hydroxide at pH = 10-11. It was proved (X-ray diffraction method) that the chosen method allows to obtain the particles of colloidal magnetite size <d> = 16 nm without impurities with the correct parameters of the crystal lattice with high magnetic properties that can be used to create drugs with magnetic properties.