Charkaoui Mouad Titrimetric micro-determination of hydroxyzine using oxone

Abstract

The reported methods (HPLC) suffer from such drawbacks as high cost, multiple steps and also several clean-up steps. They are time consuming and require organic toxic solvents. Any method chosen for the routine analysis should be reasonably simple, used materials should readily be available in the laboratory or readily obtainable and require a minimum amount of the equipment. These objectives have been fulfilled by the titrimetric procedure developed. The accuracy, reproducibility, simplicity and cost-effectiveness of the method suggest their application in the quality control laboratories where the modern and expensive instruments are not available.