Titrimetric micro-determination of therapeutically active phenothiazines using potassium caroate

Abstract

The method presented is simple, fast, accurate and precise. They are considerably more sensitive than many similar methods cited in the literature. In fact, method is the most sensitive titrimetric method ever reported for the assay of phenothiazines. Moreover, the reagent used is superior to many reagents previously used because it is available as an analytical grade reagent, has high molecular mass and is extremely stable, and can be used in acidic media.