Chronopharmacological study of hepatoprotective activity of the drug «Antral®»

Abstract

In recent years, in chronopharmacology, daily monitoring of biorhythms has become increasingly important as much more informative and clinically relevant. Antral - as a hepatoprotective agent has been successfully used in the clinical practice of Ukrainian doctors for more than 10 years, and as a drug registered in Ukraine since 1994. Evaluation of the circadianian dependence of the severity of hepatoprotective activity of antral on the background of acute toxic hepatitis simulated in four different periods of the day was performed in the third stage of experimental studies.