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http://dspace.nuph.edu.ua/handle/123456789/27237
Title: | Non-obvious effects of montelukast - Leukotriene receptor blocker: Frigoprotective and anticonvulsant properties |
Authors: | Shtrygol, S. Yu. Kapelka, I. G. Mishchenko, M. V. Mishchenko, O. Ya. |
Keywords: | montelukast;inflammation;leukotrienes;cold trauma;epilepsy |
Issue Date: | 2021 |
Bibliographic description (Ukraine): | Non-obvious effects of montelukast - Leukotriene receptor blocker: Frigoprotective and anticonvulsant properties / S. Yu. Shtrygol, I. G. Kapelka, M. V. Mishchenko, O. Ya. Mishchenko // Medicni Perspektivi. - 2021. - № 26 (2). - Р. 19-25. |
Abstract: | The participation of arachidonic acid metabolism products – prostaglandins and leukotrienes – in the process of inflammation is a common pathogenetic link of cold injury and epilepsy. Montelukast is widely used for the treatment of bronchial asthma and allergic rhinitis as a leukotriene receptor blocker. However, the mechanism of action of the drug suggests a wider range of its pharmacological properties and the corresponding scope of application. This study is aimed to determine the effectiveness of montelukast as a potential frigoprotective and anticonvulsant drug. |
URI: | http://dspace.nuph.edu.ua/handle/123456789/27237 |
Appears in Collections: | Наукові публікації кафедри клінічної фармакології ІПКСФ |
Files in This Item:
File | Description | Size | Format | |
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NON-OBVIOUS EFFECTS.pdf | 318,83 kB | Adobe PDF | View/Open |
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