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|Title:||Medicinal chemistry. Influence of physico-chemical parameters of medicinal substances on the processes of their absorption, distribution, biotransformation and interaction with receptors: Lecture for English-speaking students|
|Authors:||Перехода, Л. О.|
Perekhoda, L. O.
Гриценко, І. С.
Gritsenko, I. S.
Таран, С. Г.
Taran, S. G.
Березнякова, Н. Л.
Berezniakova, N. L.
Георгіянц, В. А.
Georgiyants, V. A.
Рахімова, М. В.
Rakhimova, M. V.
Сулейман, М. М.
Suleiman, M. M.
|Bibliographic description (Ukraine):||Medicinal chemistry. Influence of physico-chemical parameters of medicinal substances on the processes of their absorption, distribution, biotransformation and interaction with receptors: Lecture for English-speaking students / L. O. Perekhoda, I. S. Gritsenko, S. G. Taran [et al.]. – Kharkiv, 2018. - 45 p.|
|Abstract:||Medicinal chemistry, itself, is concerned mainly with the organic, analytical, and biochemical aspects of this process, but the chemist must interact productively with those in other disciplines. Thus, medicinal chemistry occupies a strategic position at the interface of chemistry and biology. All of the principles discussed in this lecture book are based on fundamental organic chemistry, physical chemistry, and biochemistry. To provide an understanding of the principles of medicinal chemistry, it is necessary to consider the physicochemical properties used to develop new pharmacologically active compounds and their mechanisms of action, the drug’s metabolism, including possible biological activities of the metabolites, the importance of stereochemistry in drug design, and the methods used to determine what “space” a drug occupies.|
|Appears in Collections:||Навчальні видання кафедри медичної хiмiї|
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