Development of 3d-printed dosage forms with rutin

Abstract

Novel aqueous PEO gel formulations loaded with plant-origin rutin were developed for pharmaceutical SSE 3D printing. The most feasible aqueous PEO gel formulation for the SSE 3D printing of rutin was composed of rutin 100 mg/ml and tween-80 50 mg/ml dissolved in a 12% aqueous PEO gel. The SSE 3D-printed dosage forms are purposed for the oral administration of rutin.