Prospects of creating orodispersible tablets based on medicinal plant raw materials

Abstract

Currently, an important issue in medicine is the therapy of neuroses and neurosis-like conditions, the growth of which is due to the number and intensity of psychotraumatic factors affecting a person in modern society. Tranquilizers, antidepressants and sedatives are widely used in the treatment of neurotic disorders and pharmacological correction of stress. The listed conditions require long-term treatment, therefore, the safety and tolerability of drugs is of particular importance. The use of synthetic drugs for the treatment of diseases of the central nervous system (CNS) is accompanied by a number of side effects: hypersedation, impaired memory and attention, metabolic, hormonal changes, the development of drug dependence, etc. These factors limit the possibility of their use. Therefore, of particular interest are preparations of plant origin used in medicine for the treatment of the above-listed conditions. Therefore, the question arises of developing a solid dosage form, namely orodispersible tablets (ODT), which contain medicinal plant raw materials as active pharmaceutical ingredients.