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Title: | Substantiation of the methods of quality control for a substance with the anticonvulsant action |
Authors: | Bevz, N. Yu. Georgiyants, V. A. Gryinenko, V. Бевз, Н. Ю. Георгіянц, В. А. Гриненко, В. Георгиянц, В. А. |
Keywords: | pharmaceutical analysis;identification;quantitative determination;acid-base titration;anticonvulsants |
Issue Date: | 2014 |
Bibliographic description (Ukraine): | Bevz, N. Yu. Substantiation of the methods of quality control for a substance with the anticonvulsant action / Natalia Bevz, Victoriya Georgiyants and Vasyl Gryinenko // Journal of Chemical and Pharmaceutical Research. - 2014. - № 6(5). - Р. 775-779. |
Abstract: | The data concerning substantiation and development of the methods of quality control for a new biologically active substance with the anticonvulsant action are presented in the article. Identification of the substance under research has been performed by physical and chemical methods (IR-, UV- and PMR-spectroscopy) and by chemical reactions. For quantitative determination of dimetpyrazine the method of acid-base titration in the non-aqueous medium has been developed. The relative uncertainty of the average is 0.51%. |
URI: | http://dspace.nuph.edu.ua/handle/123456789/6150 |
Appears in Collections: | Наукові публікації кафедри фармацевтичних технологій та забезпечення якості ІПКСФ Наукові публікації кафедри фармацевтичної хімії |
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