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http://dspace.nuph.edu.ua/handle/123456789/13298
Title: | The justification for the choice of exipients of the prepation “Corvalol” in the form of sublingual tablets |
Authors: | Омельченко, І. О. Омельченко, И. О. Omelchenko, I. O. Ярних, Т. Г. Ярных, Т. Г. Yarnykh, T. G. Борщевський, Г. І. Борщевский, Г. И. Borschevskyi/, G. I. |
Keywords: | “Corvalol”;sublingual tablets;direct compression |
Issue Date: | 2016 |
Abstract: | Based on the study of the physical properties of the tabletting mass the choice of excipients for “Corvalol” sublingual tablets by the method of direct compression has been substantiated. Three model mixtures for tablet formulations have been analyzed. It has been found that the optimal excipients are β-cyclodextrin, lactose monohydrate 80, potassium acesulfame, magnesium stearate. It has been demonstrated that the conclusions made when analysing physical parameters of the tablet formulations are confirmed by actual results of compression |
URI: | http://dspace.nuph.edu.ua/handle/123456789/13298 |
Appears in Collections: | Наукові публікації кафедри АТЛ |
Files in This Item:
File | Description | Size | Format | |
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88741-187289-1-PB.pdf | 337,99 kB | Adobe PDF | View/Open |
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