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http://dspace.nuph.edu.ua/handle/123456789/14312| Title: | Quantitative determination of ethacysine in tablets by spectrofluorometry as its sulfone |
| Authors: | Blazheyevskiy, M.Ye. Doroshenko, A. O. Yevtukhov, V. O. Блажеевский, Н. Е. Блажеєвський, М. Є. Дорошенко, А. О. Евтухов, В. О. Євтухов, В. О. |
| Keywords: | spectrofluorometry;quantitative determination;kinetic;potassium hydrogenperoxomonosulfate;ethacysine;spectrofl uorometry;quantitative determination |
| Issue Date: | 2016 |
| Bibliographic description (Ukraine): | Blazheyevskiy, M. Ye. Quantitative determination of ethacysine in tablets by spectrofluorometry as its sulfone / M. Ye. Blazheyevskiy, A. O. Doroshenko, V. O. Yevtukhov // Theoretical and applied problems of physical, mathematical and chemical sciences in the context of the social demand for the knowledge limits expansion : Peer-reviewed materials digest (collective monograph) published following the results of the CXXII International Research and Practice Conference “and I stage of the Championship in Physics and Mathematics, Chemistry, Earth and Space Sciences (London, April 27 - May 6, 2016). – London: IASHE, 2016. – P. 11-14. |
| Abstract: | The new method was elaborated for quantitative determination of ethacysine hydrochloride (the diethylamino analog of ethmozine) (ЕТ) in the form of corresponding sulfonic derivative obtained with the use of potassium hydrogenperoxomonosulphate, through the spectrofl uorometry (λex = 264 nm/ λеm = 380 nm). Linear concentration dependence was preserved in the concentrations interval (1-8)·10-6 mol/l ЕТ, lgI=97047c – 0.003 (r=0,999). LOQ =1.1·10-6 mol/l. It was showed that in the determination of ET in the tablets 50 mg (Olainfarm, Latvia) using the developed method, RSD =1.7% (accuracy, δ =- 0.2%). Keywords: kinetic, potassium hydrogenperoxomonosulfate, ethacysine, spectrofl uorometry, quantitative determination. |
| URI: | http://dspace.nuph.edu.ua/handle/123456789/14312 |
| Appears in Collections: | Наукові публікації кафедри загальної хімії |
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