Investigation of antioxidant and membranestabilizing activity of plant collection with nephroprotective properties

Abstract

The antioxidant and membrane stabilizing activity of plant collection, containing Polygoni avicularis herba, Fragariae herba, Juglandis folium, Uvae ursi folia, Urticae folia, Elymi repensis rhizomata et radices (25,0 for each) and Helichrysi arenarii Flores (20,0), has been estimated on the model of glycerolinduced acute renal failure in rats. It has been found out that the infusion (1:10) of the plant collection at a dose of 10 ml/kg suppressed lipid peroxidation processes and increased catalase activity, as well as reference drug «Chophytol» at a dose of 100 mg/kg. The original medicinal plant collection did not have the influence on the red blood cells osmotic resistance in intact animals, as well as under conditions of glycerol-induced acute renal failure.