Please use this identifier to cite or link to this item:
http://dspace.nuph.edu.ua/handle/123456789/17531| Title: | The use of the docking studies with the purpose of searching potential cardioprotectors |
| Authors: | Drapak, I. V. Perekhoda, L. O. Vynogradova, O. Protopopov, M. Suleiman, M. M. Sych, I. A. Kobzar, N. P. Kiz, O. V. Драпак, І. В. Перехода, Л. О. Виноградова, О. Протопопов, М. Сулейман, М. М. Сич, І. А. Кобзар, Н. П. Кізь, О. В. |
| Keywords: | enzyme gamma-butyrobetaine hydroxylase;cardio protective drug;derivatives of 2-imino-1,3-thiazoline;1,3,4-thiadiazole;receptor-based flexible docking |
| Issue Date: | 2018 |
| Bibliographic description (Ukraine): | The use of the docking studies with the purpose of searching potential cardioprotectors / I. Drapak, L. Perekhoda, O. Vynogradova, M. Protopopov, M. Suleiman, I. Sych, N. Kobzar, O. Kiz // Pharmacia. - 2018. - № 2. - С. 40-46. |
| Abstract: | The study is to conduct the receptor-based virtual screening of the sample of 154 compounds among derivatives of 2-imino-1,3-thiazoline (77compunds), and2,5-disubstituted derivatives of 1,3,4-thiadiazole(77compunds) to the active site of gamma-butyrobetaine hydroxylase for the directed search of inhibitors of this enzyme as potential cardio protectors |
| URI: | http://dspace.nuph.edu.ua/handle/123456789/17531 |
| Appears in Collections: | Наукові публікації кафедри медичної хiмiї |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Pharmaca.pdf | 386,18 kB | Adobe PDF | View/Open |
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