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http://dspace.nuph.edu.ua/handle/123456789/19031| Title: | Predictive technologies in the study of 1,3-thiazoline derivatives |
| Authors: | Zolotarova, D.R. Yeromina, Z. G. Єрьоміна, З. Г. Еремина, З. Г. |
| Issue Date: | 2019 |
| Bibliographic description (Ukraine): | Zolotarova D.R. T Predictive technologies in the study of 1,3-thiazoline derivatives / D.R. Zolotarova, Z.G. Ieromina // Topical issues of new medicines development: матеріали XXVI Міжнародної науково-практичної конференції молодих учених та студентів (10-12 квіт. 2019 р., м. Харків). – Харків: НФаУ, 2019. – С. -34 |
| Abstract: | To continue the search of new biologically active substances among 1,3-thiazole derivatives and to optimize the pharmacological screening of 1,3-thiazoline derivatives, namely 4-aryl-3-[3- (morpholin-4-yl)propyl]-N-phenyl-1,3-thiazol-2(3H)-imine derivatives using predictive technologies. |
| Description: | According to the test results, determined «drug-like» properties are in the range of permissible values for all test compounds and comply with requirements Lipinski. Results of GUSAR-prognosis indicates that the compounds probably belong to class 4 and 5 of toxicity (low-toxic and practically non-toxic substances). All compounds synthesized comply with requirements Lipinski and probably belong to low-toxic and practically non-toxic substances, so can be recommended for experimental biological tests. |
| URI: | http://dspace.nuph.edu.ua/handle/123456789/19031 |
| Appears in Collections: | Патенти та винаходи кафедри фармацевтичної хiмiї |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| тези студ конф 2019 Yeromina HO.pdf | 431,7 kB | Adobe PDF | View/Open |
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