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http://dspace.nuph.edu.ua/handle/123456789/21038| Title: | Hydrolytic opening of the quinazoline ring in 3-furfuryl-4-oxo3,4-dihydroquinazoline derivatives |
| Authors: | Shemchuk, L. A. Chernykh, V. P. Levashov, D. V. Sytnik, K. M. Шемчук, Л. А. Черних, В. П. Левашов, Д. В. Ситнік, К. М. Шемчук, Л. А. Черных, В. П. Левашов, Д. В. Сытник, К. М. |
| Issue Date: | 2010 |
| Bibliographic description (Ukraine): | Hydrolytic opening of the quinazoline ring in 3-furfuryl-4-oxo3,4-dihydroquinazoline derivatives / L. A. Shemchuk, V. P. Chernykh, D. V. Levashov, K. M. Sytnik // Russian journal of organic chemistry. – 2010. - Vol. 46, № 8. - Р. 1243-1245. doі : 10.1134/S1070428010080208 |
| Abstract: | Ethyl 3-furfuryl-4-oxo-3,4-dihydroquinazoline-2-carboxylate extremely readily undergoes hydrolysis in acid, alkaline, or neutral medium with formation of 2-(2-ethoxy-1,2-dioxoethylamino)-N-furfurylbenzamide. The reaction of ethyl 3-furfuryl-4-oxo-3,4-dihydroquinazoline-2-carboxylate with phenylmagnesium bromide yields N-furfuryl-2-(2-hydroxy-2,2-diphenyl-1-oxoethylamino)benzamide as a result of hydrolytic cleavage of the quinazoline ring. |
| URI: | http://dspace.nuph.edu.ua/handle/123456789/21038 |
| Appears in Collections: | Наукові публікації В. П. Черних |
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