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http://dspace.nuph.edu.ua/handle/123456789/21143| Title: | Features of frequency distribution of immunogenetic markers of class 1 hla in children with type 1 diabetes in combination with thyroid pathology introduction |
| Authors: | Eremenko, R. F. Еременко, Р. Ф. Єрьоменко, Р. Ф. Ковальова, В. І. Ковалева, В. И. Kovaleva, V. I. |
| Keywords: | HLA;diabetes mellitus type 1;thyroid pathology;children |
| Issue Date: | 2019 |
| Bibliographic description (Ukraine): | Eremenko, R. F. Features of frequency distribution of immunogenetic markers of class 1 hla in children with type 1 diabetes in combination with thyroid pathology introduction / R. F. Eremenko, V. I. Kovalоva // Biological Markers in fundamental and clinical medicine, Prague, November 7-9, 2019. – Prague, 2019. – C. 112-113. |
| Abstract: | has been established [1] that the genetic base of diabetes mellitus (DM) type 1 is on 70% determined by the HLA (Human Leukocyte Antigens) genes. No other genetic area alone determines the risk of developing a disease compared to the HLA system. According to the available data [2], autoimmune diseases of the thyroid gland and type 1 DM represent autoimmune syndromes of the unknown etiology with common immunological defects (target cells, thyrocytes and cells of the islets of Langerhans, excessively produce some proteins encoded by the HLA system – HLA of class 1, HLA of class 2 and transporter associated with antigen processing protein (TAP-1)). |
| URI: | http://dspace.nuph.edu.ua/handle/123456789/21143 |
| Appears in Collections: | Матеріали конференцій кафедри клiнiчної лабораторної дiагностики |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 248-Article Text-480-1-10-20191105.pdf | 196,54 kB | Adobe PDF | View/Open |
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