Please use this identifier to cite or link to this item:
http://dspace.nuph.edu.ua/handle/123456789/22388| Title: | Study of biopharmaceutical solubility of thioctic acid |
| Authors: | Ковалевська, І. В. Рубан, О. А. Грудько, В. О. Kovalevska, I. V. Ruban, O. A. Grudko, V. O. Рубан, Е. А. |
| Keywords: | biopharmaceutical solubility;thioctic acid;solid dispersion;spectrophotometric determination |
| Issue Date: | 2019 |
| Bibliographic description (Ukraine): | Kovalevska, I. V. Study of biopharmaceutical solubility of thioctic acid / I. V. Kovalevska, O. A. Ruban, V. O. Grudko // Pharmakeftiki. - 2019. - № 3. - Р. 47-53. |
| Abstract: | Thioctic acid is an endogenous vitamin-like substance that acts as a coenzyme and participates in the oxidative decarboxylation of α-ketoacids. It is widely used in the treatment of type II diabetes mellitus . According to literature, the relative bioavailability of thioctic acid in the oral use of solid dosage forms is more than 60% in proportion to the drinking solution. The establishment of biopharmaceutical solubility is a necessary step in the development of the composition and technology of medicines. |
| URI: | http://dspace.nuph.edu.ua/handle/123456789/22388 |
| Appears in Collections: | Наукові публікації кафедри промислової технологiї лiкiв та косметичних засобів |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| стаття Греція - НФаУ Кафедра заводської технології ліків.pdf | Study of biopharmaceutical solubility of thioctic acid | 1,18 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.