Research of the choice of the basis of a semi-solid medicine with a semi-solid extract of feverfew (Tanacetum parthenium)

Abstract

Medicines created with the use of substances iso- lated from plant raw materials have been attracting atten- tion for many decades. The Ukrainian market of herbal

medicines is also characterized by a significant range.

This is due to the fact that Ukraine has always been fa- mous for the richness of the plant world and a serious

scientific base, which has a huge potential of scientists and researchers in the field of medicine and pharmacy. It provides opportunities for the isolation of biologically active substances from medicinal plant raw materials in order to create on their basis modern domestic drugs. In recent years, a number of scientific works by Ukrainian scientists have been devoted to the study of the chemical composition and pharmacological activity of little-studied medicinal plants. At the Department of Botany of National University of Pharmacy (NUPh), under the leadership of prof. Gontova T.M., obtained a semi-solid extract of feverfew (SSFE) of the Asteraceae

family and confirmed a high content of phenolic sub- stances in the classes of hydroxycinnamic acids, namely

3,5-dicafeoiloquine (1.575 %), 4,5-dicafeoiloquine

(1.308 %) and chlorogenic (0.784 %) acid and sesquiter- pene lactones. Among flavonoids, apigenin-7-glucoside

(0.071 %) and kaempferol (0.041 %) were found