Study of stability and determination of residual quantity of organic solvent in lipophilic extract of pumpkin

Abstract

Important indicators of medicines' quality are stability and shelf life, that is, the time during which no negative changes in the physico-chemical, pharmacological and consumer characteristics of the product are observed. When developing the composition of a new substance or a drug, the shelf life is determined experimentally, by periodically evaluating all indicators included into the methods of quality control. To establish the qualitative characteristics of the pumpkin extract, the appearance, solubility, identification, microbiological purity, and quantitative content of active substances in the extract were evaluated. To determine the residual amount of organic solvent in the extract, the method of gas-liquid chromatography was used.