Effect of complex pharmaceutical composition at the histostructure of the pancreas under the conditions of experimental metabolic syndrome in rats

Abstract

Metabolic syndrome (MetS) – it is a symptom complex characterized by insulin resistance, impaired prooxidant-antioxidant balance of the body with the development of subchronic inflammation, dyslipidemia and is a predictor of cardiovascular diseases and type 2 diabetes mellitus (T2DM). It was found that MetS causes a 5-fold increase in the risk of developing T2DM, a 2-fold risk of developing cardiovascular diseases over the next 5 to 10 years, 2-4 times increases the risk of stroke, 3-4 times myocardial infarction and twice the risk of death. Given the above, timely prevention and treatment of MetS is an important task.