Синтез 2-(алкилтио)-5,6,7,8- тетрагидро[1]бензотиено[2,3-d]пиримидин-4(3H)-онов и прогноз их биологической активности

Abstract

The synthesis of potentially biologically active 2-(alkylthio)-5,6,7,8- tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-ones was planned and carried out. Prediction of the pharmacological activity of the synthesized molecules showed their potential for antimicrobial activity, and for ethyl [(4-oxo-3-phenyl-3,4,5,6,7,8- hexahydro[1]benzothieno[2,3-d]pyrimidine-2-yl)thio]acetate the possibility of anti- inflammatory activity.