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http://dspace.nuph.edu.ua/handle/123456789/35759| Title: | Development of the metabolic pathway scheme of a novel anticonvulsant based on the results of metabolic study in human liver microsomes |
| Authors: | Demko, A. Severina, H. Sikanen, T. Järvinen, P. Georgiyants., V. |
| Issue Date: | 2025 |
| Publisher: | НФаУ |
| Bibliographic description (Ukraine): | Development of the metabolic pathway scheme of a novel anticonvulsant based on the results of metabolic study in human liver microsomes / A. Demko [et al.] // Modern chemistry of medicines : матеріали Міжнар. internet-конф., м. Харків, 27 лис. 2025 р. Харків : НФаУ, 2025. С. 20. |
| Abstract: | The examination of metabolic pathways for novel pharmacologically active compounds is an essential phase in their preclinical safety and efficacy assessment. This study aimed to identify the primary metabolic transformation routes of the promising anticonvulsant 2-(2,4-dioxo1,4-dihydroquinazolin-3(2H)-yl)-N-[(2,4 dichlorophenyl)methyl]acetamide (MaIO 168) within the human liver microsomal (HLM) system |
| URI: | http://dspace.nuph.edu.ua/handle/123456789/35759 |
| Appears in Collections: | Наукові публікації кафедри фармацевтичної хімії |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 98_100_ Modern chemistry of medicines 2025 20.pdf | 677,65 kB | Adobe PDF | View/Open |
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