Justification of the composition of buccal films with kalanchoe juice

Abstract

Introduction. Periodontal tissue disease is a common dental problem in both adults and children, against the background of untimely consultation with a doctor. Herbal medicines are distinguished in a separate group of medicines with different types of action among the pharmaceuticals for treating inflammation of the oral mucosa and gums. These medicines have a high pharmacological effect; their administration is almost not accompanied by side effects. The phytopreparation prescribed for aphthous stomatitis and gingivitis treatment is Kalanchoe juice from the plant Kalanchoe pinnata (genus Kalanchoe), which has anti-inflammatory activity, also helps cleanse wounds of necrotic tissues, and stimulates their healing. Kalanchoe juice is applied to the oral mucosa 3−4 times a day in the form of applications, which is uncomfortable when used. Buccal films are the perspective drug delivery system due to their ability to deliver drugs directly to the place of the action in the oral cavity, and they are capable of facilitating local delivery. Mucoadhesive buccal films are the preferred dosage form amongst patients, owing to their superior flexibility which enhances comfort.