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|Title:||Formulation of sustained release matrix tablets as an approach to improve antidiabetic efficacy of Vaccinium myrtillus leaf extract|
|Authors:||Kolisnyk, T. Ye.|
Ruban, O. A.
Slipchenko, H. D.
Колісник, Т. Є.
Колесник, Т. Е.
Рубан, О. А.
Рубан, Е. А.
Слипченко, Г. Д.
Сліпченко, Г. Д.
|Keywords:||vaccinium myrtillus;matrix tablets|
|Bibliographic description (Ukraine):||Kolisnyk, T. Ye. Formulation of sustained release matrix tablets as an approach to improve antidiabetic efficacy of Vaccinium myrtillus leaf extract / T. Ye. Kolisnyk, O. A. Ruban, G. D. Slipchenko // Science and Practice 2018 : book of abstracts of 9th International Pharmaceutical Conference, Kaunas, November 9, 2018. - Kaunas : Lithuanian University of Health Sciences. - 2018. - P. 42.|
|Abstract:||Bilberry (Vaccinium myrtillus) leaves belong to promising sources of natural antidiabetic drugs. Bilberry leaf extracts (BLEs) were found to inhibit small intestine enzymes participating in carbohydrate digestion that prevents glucose absorption and decreases glycemic level. Hence, the development of a sustained release (SR) formulation was suggested as an approach to increase the efficacy of BLE. This should contribute to the prolongation of half-life and increasing small intestine concentrations of bilberry leaf polyphenols.|
|Appears in Collections:||Наукові публікації кафедри ЗТЛ|
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