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http://dspace.nuph.edu.ua/handle/123456789/22388Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Ковалевська, І. В. | - |
| dc.contributor.author | Рубан, О. А. | - |
| dc.contributor.author | Грудько, В. О. | - |
| dc.contributor.author | Kovalevska, I. V. | - |
| dc.contributor.author | Ruban, O. A. | - |
| dc.contributor.author | Grudko, V. O. | - |
| dc.contributor.author | Рубан, Е. А. | - |
| dc.date.accessioned | 2020-04-28T20:42:00Z | - |
| dc.date.available | 2020-04-28T20:42:00Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.citation | Kovalevska, I. V. Study of biopharmaceutical solubility of thioctic acid / I. V. Kovalevska, O. A. Ruban, V. O. Grudko // Pharmakeftiki. - 2019. - № 3. - Р. 47-53. | uk_UA |
| dc.identifier.uri | http://dspace.nuph.edu.ua/handle/123456789/22388 | - |
| dc.description.abstract | Thioctic acid is an endogenous vitamin-like substance that acts as a coenzyme and participates in the oxidative decarboxylation of α-ketoacids. It is widely used in the treatment of type II diabetes mellitus . According to literature, the relative bioavailability of thioctic acid in the oral use of solid dosage forms is more than 60% in proportion to the drinking solution. The establishment of biopharmaceutical solubility is a necessary step in the development of the composition and technology of medicines. | uk_UA |
| dc.language.iso | en | uk_UA |
| dc.subject | biopharmaceutical solubility | uk_UA |
| dc.subject | thioctic acid | uk_UA |
| dc.subject | solid dispersion | uk_UA |
| dc.subject | spectrophotometric determination | uk_UA |
| dc.title | Study of biopharmaceutical solubility of thioctic acid | uk_UA |
| dc.type | Article | uk_UA |
| Appears in Collections: | Наукові публікації кафедри промислової технологiї лiкiв та косметичних засобів | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| стаття Греція - НФаУ Кафедра заводської технології ліків.pdf | Study of biopharmaceutical solubility of thioctic acid | 1,18 MB | Adobe PDF | View/Open |
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