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Title: The phytochemical and chemotaxonomic study of Salvia spp. growing in Ukraine
Authors: Koshovyi, O. M.
Raal, Ain
Kovaleva, A. M.
Myha, M. M.
Ilina, T. V.
Borodina, N. V.
Komissarenko, A. M.
Кошовий, О. М.
Рааль, Айн
Ковальова, А. М.
Мига, М. М.
Ільїна, Т. В.
Бородіна, Н. В.
Комісаренко, А. М.
Ковалева, А. М.
Комиссаренко, А. Н.
Кошевой, О. Н.
Рааль, Айн
Мига, М. М.
Ильина, Т. В.
Бородина, Н. В.
Keywords: sage;chemotaxonomy;terpenoids;polyphenols;gas chromatography;HPLC
Issue Date: 2020
Publisher: Journal of Applied Biology & Biotechnology
Bibliographic description (Ukraine): The phytochemical and chemotaxonomic study of Salvia spp. growing in Ukraine / O. M. Koshovyi, A. Raal, A. M. Kovaleva, M. M. Myha, T. V. Ilina, N. V. Borodina, A. M. Komissarenko // Journal of Applied Biology & Biotechnology. - 2020. - Vol. 8 (03). - P. 29-36.
Abstract: Salvia officinalis is a well-studied and popular medicinal plant containing toxic thujones, rather limited phytochemical and pharmacological studies have been performed on other Salvia spp. The aim of the study was to perform phytochemical and chemotaxonomic studies of Salvia genus species (n = 16) from Ukraine to identify the most promising species for the pharmaceutical industry. The content of essential oils from the leaves of 16 Salvia spp. has been studied by gas chromatography/mass spectrometry (MS) and polyphenols by high performance liquid chromatography/MS, and a chemotaxonomic study has been performed by calculation of coefficients of occurrence, originality, and pair affinity. The Salvia spp. is characterized by the presence of monoterpenoids, hydroxycinnamic acids – derivatives of caffeic acid, and flavonoids – derivatives of luteolin and apigenin. The highest content of essential oil is observed in the leaves of S. officinalis, S. grandiflora, and S. scabiosifolia (1.41%–1.85%). The highest amount of hydroxycinnamic acids is in the leaves of S. pratensis, S. illuminata, S. austriaca, and S. verticillata; the highest content of flavonoids and phenolic compounds is found in the leaves of S. grandiflora, S. pratensis, S. illuminata, S. nemorosa, S. pendula, S. sylvestris, S. nutans, S. verticillata, and S. cernua. The chemical profile of the genus has been determined; it is characterized by terpenoids such as α- and β-pinene, camphane derivatives (camphene, camphor, and borneol), p-cymene, 1,8-cineol, limonene, phenolic compounds (caffeic and rosmarinic acids), and flavonoids (cynaroside, cosmosiin, hispidulin, and cirsimaritin). A rather high concentration of toxic _- and _-thujone is typical only in the essential oil of S. officinalis (33.6% and 6.5%, respectively). The most promising species for use in the pharmaceutical industry are S. grandiflora, S. cernua, S.pratensis, S. nemorosa, and S. verticillata.
Appears in Collections:Наукові публікації кафедри фармакогнозії

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